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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560223Generated: November 2, 2026

Thioacetamide → 2-Methyl-5-p-tolyl-thiazole-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/560223

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioacetamideHCID 2723949—
ReactantMethyl 3-chloro-2-oxo-3-(p-tolyl)propanoateHCID 57437153—
Product2-Methyl-5-p-tolyl-thiazole-4-carboxylic acid methyl esterHCID 53271193—

Reaction Steps

prepared by reaction of 3-chloro-2-oxo-3-p-tolyl-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.92 min; [M+H]+=248.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-3b4f4a9f7aa949648c0b0393c1b0077d
Source noteuspto-grants-2011_11