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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560228Generated: October 30, 2026

Thioacetamide → 2-Methyl-5-(3-trifluoromethyl-phenyl)-thiazole-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/560228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioacetamideHCID 2723949—
ReactantHCID 20064726HCID 20064726—
Product2-Methyl-5-(3-trifluoromethyl-phenyl)-thiazole-4-carboxylic acid methyl esterHCID 57437166—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-trifluoromethyl-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.98 min; [M+H]+=302.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-24cb67a554124c3c9ff4ade90c9ec46b
Source noteuspto-grants-2011_11