HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thioacetamide → 5-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thioacetamide | HCID 2723949 | — |
| Reactant | 3-Chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester | HCID 64898287 | — |
| Product | 5-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester | HCID 66865670 | — |
Reaction Steps
prepared by reaction of 3-chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=1.00 min; [M+H]+=266.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063099B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-df956139ba0643a6aade6e904b6613b8 |
| Source note | uspto-grants-2011_11 |