3-Tolylboronic acid → 2-m-Tolyl-thiophene-3-carboxylic Acid

HRID 560329Notes

Reaction equation

HRID 560329 reaction equation
Br[C:2]1[S:3][CH:4]=[CH:5][C:6]=1[C:7]([OH:9])=[O:8].[C:10]1([CH3:19])[CH:15]=[CH:14][CH:13]=[C:12](B(O)O)[CH:11]=1>>[C:10]1([CH3:19])[CH:15]=[CH:14][CH:13]=[C:12]([C:2]2[S:3][CH:4]=[CH:5][C:6]=2[C:7]([OH:9])=[O:8])[CH:11]=1

Participants

3

Reactant 2

HCID 27339503-Tolylboronic acidHCID 123209712-Bromothiophene-3-carboxylic acid

Product 1

HCID 669984252-m-Tolyl-thiophene-3-carboxylic Acid

Procedure

prepared by reaction of 2-bromo-thiophene-3-carboxylic acid with m-tolylboronic acid. LC-MS (basic): tR=0.51 min; [M−H]−=217.3.

Sources & evidence

ORD record
ord-720465a9660144d3bc054c897875d0ac
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

Loading…