2,3-Dihydrothieno(3,4-b)(1,4)dioxine-5-carboxylic acid → HCID 66998565, compound

HRID 560344Notes

Reaction equation

HRID 560344 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][C@H:12]2[C@H:10]([CH2:11]2)[C@H:9]1[CH2:14][NH2:15])=[O:7])([CH3:4])([CH3:3])[CH3:2].[O:16]1[CH2:21][CH2:20][O:19][C:18]2=[C:22]([C:25](O)=[O:26])[S:23][CH:24]=[C:17]12>>[C:1]([O:5][C:6]([N:8]1[CH2:13][C@H:12]2[C@H:10]([CH2:11]2)[C@H:9]1[CH2:14][NH:15][C:25]([C:22]1[S:23][CH:24]=[C:17]2[C:18]=1[O:19][CH2:20][CH2:21][O:16]2)=[O:26])=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 64838802,3-Dihydrothieno(3,4-b)(1,4)dioxine-5-carboxylic acidHCID 59444330tert-butyl (1S,2S,5R)-2-(aminomethyl)-3-azabicyclo(3.1.0)hexane-3-carboxylate

Product 1

HCID 66998565HCID 66998565, compound

Procedure

prepared by reaction of (1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester with 2,3-Dihydro-thieno[3,4-b][1,4]dioxine-5-carboxylic acid. LC-MS: tR=0.96 min; [M+H]+=381.1.

Sources & evidence

ORD record
ord-c2d3594c6eec4afe8cdb073990223879
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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