HCID 58828767, compound → HCID 86644209, compound

HRID 560351Notes

Reaction equation

HRID 560351 reaction equation
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:7][NH:8][C:9](=[O:14])[C:10]([F:13])([F:12])[F:11].[C:15]1([CH3:29])[CH:20]=[CH:19][C:18]([C:21]2[S:22][CH:23]=[CH:24][C:25]=2[C:26](O)=[O:27])=[CH:17][CH:16]=1>>[F:13][C:10]([F:12])([F:11])[C:9]([NH:8][CH2:7][C@H:2]1[N:3]([C:26]([C:25]2[CH:24]=[CH:23][S:22][C:21]=2[C:18]2[CH:19]=[CH:20][C:15]([CH3:29])=[CH:16][CH:17]=2)=[O:27])[CH2:4][C@H:5]2[C@@H:1]1[CH2:6]2)=[O:14]

Participants

3

Reactant 2

HCID 58828767HCID 58828767, compoundHCID 59444331N-[(1S,2S,5R)-1-(3-Aza-bicyclo[3.1.0]hex-2-yl)methyl]-2,2,2-trifluoro-acetamide

Product 1

HCID 86644209HCID 86644209, compound

Procedure

prepared by reaction of N-[(1S,2S,5R)-1-(3-Aza-bicyclo[3.1.0]hex-2-yl)methyl]-2,2,2-trifluoro-acetamide with 2-p-tolyl-thiophene-3-carboxylic acid.

Sources & evidence

ORD record
ord-34e18c396d454d89b9de89c793f762a8
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

Loading…