N-[(1S,2S,5R)-1-(3-Aza-bicyclo[3.1.0]hex-2-yl)methyl]-2,2,2-trifluoro-acetamide → HCID 86644210, compound

HRID 560352Notes

Reaction equation

HRID 560352 reaction equation
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:7][NH:8][C:9](=[O:14])[C:10]([F:13])([F:12])[F:11].[C:15]1([CH3:29])[CH:20]=[CH:19][CH:18]=[C:17]([C:21]2[S:22][CH:23]=[CH:24][C:25]=2[C:26](O)=[O:27])[CH:16]=1>>[F:13][C:10]([F:12])([F:11])[C:9]([NH:8][CH2:7][C@H:2]1[N:3]([C:26]([C:25]2[CH:24]=[CH:23][S:22][C:21]=2[C:17]2[CH:16]=[C:15]([CH3:29])[CH:20]=[CH:19][CH:18]=2)=[O:27])[CH2:4][C@H:5]2[C@@H:1]1[CH2:6]2)=[O:14]

Participants

3

Reactant 2

HCID 59444331N-[(1S,2S,5R)-1-(3-Aza-bicyclo[3.1.0]hex-2-yl)methyl]-2,2,2-trifluoro-acetamideHCID 669984252-m-Tolyl-thiophene-3-carboxylic Acid

Product 1

HCID 86644210HCID 86644210, compound

Procedure

prepared by reaction of N-[(1S,2S,5R)-1-(3-Aza-bicyclo[3.1.0]hex-2-yl)methyl]-2,2,2-trifluoro-acetamide with 2-m-tolyl-thiophene-3-carboxylic acid.

Sources & evidence

ORD record
ord-1eb4872991b941edb7229a169eefb7c6
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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