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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560360Generated: October 29, 2026

5-(4-Ethyl-phenyl)-2-methyl-thiazole-4-carboxylic acid → Benzofuran-4-carboxylic acid{(1s,2s,5r)-3-[5-(4-ethyl-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

https://huagongshe.com/reaction/560360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Ethyl-phenyl)-2-methyl-thiazole-4-carboxylic acidHCID 57437163—
ReactantBenzofuran-4-carboxylic acid[(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amideHCID 66998521—
ProductBenzofuran-4-carboxylic acid{(1s,2s,5r)-3-[5-(4-ethyl-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amideHCID 25182530—

Reaction Steps

prepared by reaction of benzofuran-4-carboxylic acid[(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 5-(4-ethyl-phenyl)-2-methyl-thiazole-4-carboxylic acid. LC-MS (basic): tR=0.93 min; [M+H]+=486.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-7f1e5fb2d2a940ec936365413b89077d
Source noteuspto-grants-2011_11