HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Amino-thiazol-4-yl)-benzoic acid → 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid{(1s,2s,5r)-3-[2-(2-amino-thiazol-4-yl)-benzoyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Amino-thiazol-4-yl)-benzoic acid | HCID 1409773 | — |
| Reactant | 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide | HCID 66997846 | — |
| Product | 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid{(1s,2s,5r)-3-[2-(2-amino-thiazol-4-yl)-benzoyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide | HCID 87229799 | — |
Reaction Steps
prepared by reaction of 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 2-(2-Amino-thiazol-4-yl)-benzoic acid. LC-MS (basic): tR=1.15 min; [M+H]+=479.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063099B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-603d5a17dfc14fda829e9021d3d7e942 |
| Source note | uspto-grants-2011_11 |