2-phenyl-1,6-naphthyridine-3-carboxylic Acid → HCID 25183715, compound

HRID 560388Notes

Reaction equation

HRID 560388 reaction equation
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:7][NH:8][C:9]([C:11]1[N:18]2[C:14]([S:15][CH:16]=[CH:17]2)=[N:13][C:12]=1[CH3:19])=[O:10].[C:20]1([C:26]2[C:35]([C:36](O)=[O:37])=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[N:31][CH:32]=3)[N:27]=2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:20]1([C:26]2[C:35]([C:36]([N:3]3[CH2:4][C@H:5]4[C@H:1]([CH2:6]4)[C@H:2]3[CH2:7][NH:8][C:9]([C:11]3[N:18]4[C:14]([S:15][CH:16]=[CH:17]4)=[N:13][C:12]=3[CH3:19])=[O:10])=[O:37])=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[N:31][CH:32]=3)[N:27]=2)[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 27609242-phenyl-1,6-naphthyridine-3-carboxylic AcidHCID 669978466-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide

Product 1

HCID 25183715HCID 25183715, compound

Procedure

prepared by reaction of 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid[(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 2-Phenyl-[1,6]naphthyridine-3-carboxylic acid. LC-MS (basic): tR=1.20 min; [M+H]+=509.1.

Sources & evidence

ORD record
ord-d3bf74706bad4a15b465847fe5f4d9b6
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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