6-Chloro-2-phenylimidazo[1,2-a]pyridine-3-carboxylic acid → HCID 25183716, compound

HRID 560390Notes

Reaction equation

HRID 560390 reaction equation
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:7][NH:8][C:9]([C:11]1[N:18]2[C:14]([S:15][CH:16]=[CH:17]2)=[N:13][C:12]=1[CH3:19])=[O:10].[Cl:20][C:21]1[CH:22]=[CH:23][C:24]2[N:25]([C:27]([C:36](O)=[O:37])=[C:28]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[N:29]=2)[CH:26]=1>>[Cl:20][C:21]1[CH:22]=[CH:23][C:24]2[N:25]([C:27]([C:36]([N:3]3[CH2:4][C@H:5]4[C@H:1]([CH2:6]4)[C@H:2]3[CH2:7][NH:8][C:9]([C:11]3[N:18]4[C:14]([S:15][CH:16]=[CH:17]4)=[N:13][C:12]=3[CH3:19])=[O:10])=[O:37])=[C:28]([C:30]3[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=3)[N:29]=2)[CH:26]=1

Participants

3

Reactant 2

HCID 107786106-Chloro-2-phenylimidazo[1,2-a]pyridine-3-carboxylic acidHCID 669978466-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1s,2s,5r)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide

Product 1

HCID 25183716HCID 25183716, compound

Procedure

prepared by reaction of 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid[(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 6-Chloro-2-phenyl-imidazo[1,2-a]pyridine-3-carboxylic acid.

Sources & evidence

ORD record
ord-1e55f344fc224719950cb5308271f53e
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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