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HRID 560420作成日：2026年10月25日

3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid → 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide

https://huagongshe.com/reaction/560420

反応式

関与物質

役割名称HCID仕込み量
反応物3-Methylimidazo[2,1-b]thiazole-2-carboxylic acidHCID 56965725—
反応物((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 66998654—
生成物3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amideHCID 25182533—

反応手順

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid. LC-MS (basic): tR=0.82 min; [M+H]+=492.3.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08063099B2
出典データセットuspto-grants-2011_11
ORD IDord-ce4470bdefe243388be80ab8e7b77e31
出典メモuspto-grants-2011_11