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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 560432생성일: 2026년 10월 25일

1,3-dimethyl-1H-pyrazole-4-carboxylic acid → 1,3-Dimethyl-1h-pyrazole-4-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

https://huagongshe.com/reaction/560432

반응식

참여 물질

역할이름HCID투입량
반응물1,3-dimethyl-1H-pyrazole-4-carboxylic acidHCID 1273304—
반응물((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanoneHCID 66998493—
생성물1,3-Dimethyl-1h-pyrazole-4-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amideHCID 25182105—

반응 단계

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 1,3-Dimethyl-1H-pyrazole-4-carboxylic acid. LC-MS (basic): tR=0.78 min; [M+H]+=470.3.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08063099B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-d4fad28e80724eeb9c80a47ea47650c1
출처 메모uspto-grants-2011_11