HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluoro-1-methyl-1H-indole-2-carboxylic acid → 5-Fluoro-1-methyl-1h-indole-2-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluoro-1-methyl-1H-indole-2-carboxylic acid | HCID 662546 | — |
| Reactant | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone | HCID 66998493 | — |
| Product | 5-Fluoro-1-methyl-1h-indole-2-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide | HCID 25182525 | — |
Reaction Steps
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 5-Fluoro-1-methyl-1H-indole-2-carboxylic acid. LC-MS (basic): tR=0.99 min; [M+H]+=523.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063099B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-2144468050ef486c85308b86a71095cc |
| Source note | uspto-grants-2011_11 |