2,3-Dihydro-1-benzofuran-4-carboxylic acid → 2,3-Dihydro-benzofuran-4-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

Participants

Role	Name	HCID	Charge
Reactant	2,3-Dihydro-1-benzofuran-4-carboxylic acid	HCID 18787444	—
Reactant	[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone	HCID 86644211	—
Product	2,3-Dihydro-benzofuran-4-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide	HCID 25182669	—

Reaction Steps

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2 S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 2,3-Dihydro-benzofuran-4-carboxylic acid. LC-MS (basic): tR=0.79 min; [M+H]+=479.4.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08063099B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-92e75f13cce04ac3b8d47a173d26ccde
Source note	uspto-grants-2011_11