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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560457Generated: October 27, 2026

3-Chlorobenzoic Acid → N-{(1S,2S,5R)-3-[2-Amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-3-chloro-benzamide

https://huagongshe.com/reaction/560457

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chlorobenzoic AcidHCID 447—
Reactant[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanoneHCID 86644211—
ProductN-{(1S,2S,5R)-3-[2-Amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-3-chloro-benzamideHCID 25182829—

Reaction Steps

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 3-Chloro-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-85c1b8d296824618bbd42d72c4c1cc64
Source noteuspto-grants-2011_11