1,3-dimethyl-1H-pyrazole-4-carboxylic acid → 1,3-Dimethyl-1h-pyrazole-4-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1,3-dimethyl-1H-pyrazole-4-carboxylic acid	HCID 1273304	—
Edukt	[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone	HCID 86644211	—
Produkt	1,3-Dimethyl-1h-pyrazole-4-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide	HCID 87229700	—

Reaktionsschritte

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 1,3-Dimethyl-1H-pyrazole-4-carboxylic acid. LC-MS (basic): tR=0.69 min; [M+H]+=455.2.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08063099B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-ecd8891327934f3892146735d045d4d8
Quellennotiz	uspto-grants-2011_11