2,8-dimethylimidazo[1,2-a]pyridine-3-carboxylic acid → HCID 87229959, compound

HRID 560472Notes

Reaction equation

HRID 560472 reaction equation
[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[CH2:14][C@H:13]3[C@H:11]([CH2:12]3)[C@H:10]2[CH2:15][NH2:16])=[O:8])[N:6]=1.[CH3:24][C:25]1[N:26]=[C:27]2[C:32]([CH3:33])=[CH:31][CH:30]=[CH:29][N:28]2[C:34]=1[C:35](O)=[O:36]>>[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[CH2:14][C@H:13]3[C@H:11]([CH2:12]3)[C@H:10]2[CH2:15][NH:16][C:35]([C:34]2[N:28]3[CH:29]=[CH:30][CH:31]=[C:32]([CH3:33])[C:27]3=[N:26][C:25]=2[CH3:24])=[O:36])=[O:8])[N:6]=1

Participants

3

Reactant 2

HCID 27362592,8-dimethylimidazo[1,2-a]pyridine-3-carboxylic acidHCID 86644211[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone

Product 1

HCID 87229959HCID 87229959, compound

Procedure

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 2,8-Dimethyl-imidazo[1,2-a]pyridine-3-carboxylic acid.

Sources & evidence

ORD record
ord-d02bb6cb486e45c88a0126f1a6abc632
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

Loading…