HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Fluoro-2-methoxybenzoic acid → 5-Fluoro-2-methoxy-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Fluoro-2-methoxybenzoic acid | HCID 2737364 | — |
| Edukt | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone | HCID 66998654 | — |
| Produkt | 5-Fluoro-2-methoxy-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-benzamide | HCID 66997901 | — |
Reaktionsschritte
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 5-Fluoro-2-methoxy-benzoic acid. LC-MS (basic): tR=0.92 min; [M+H]+=480.1.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08063099B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-dda8f447a3c94ad88aa99e205b2ca4f7 |
| Quellennotiz | uspto-grants-2011_11 |