N-[2-(5-bromo-3-chloropyridin-2-yl)-2-(methoxyimino)ethyl]-2-(trifluoromethyl)benzamide → HCID 141385424, compound

HRID 56050Notes

Reaction equation

HRID 56050 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([Cl:26])[C:5]([C:8](=[N:23][O:24][CH3:25])[CH2:9][NH:10][C:11](=[O:22])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:21])([F:20])[F:19])=[N:6][CH:7]=1>C(#N)C>[Br:1][C:2]1[CH:3]=[C:4]([Cl:26])[C:5](/[C:8](=[N:23]\[O:24][CH3:25])/[CH2:9][NH:10][C:11](=[O:22])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:18]([F:20])([F:19])[F:21])=[N:6][CH:7]=1

Participants

3

Reactant 1

HCID 118071567N-[2-(5-bromo-3-chloropyridin-2-yl)-2-(methoxyimino)ethyl]-2-(trifluoromethyl)benzamide

Product 1

HCID 141385424HCID 141385424, compoundYield 44.1%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

143 mg of N-[2-(5-bromo-3-chloropyridin-2-yl)-2-(methoxyimino)ethyl]-2-(trifluoromethyl)benzamide was dissolved in 3 ml of acetonitrile, and the solution was irradiated with light for 12 hours in a quartz cell (manufactured by Fine, 4 clear windows for spectroscopy) using a 100 W high-pressure mercury lamp (manufactured by USHIO INC., lamp: UM-102, power supply: UM-103B-B). After completion of the reaction, the solvent was evaporated under reduced pressure, and the resulting residue was washed with 10 ml of hexane to obtain 63 mg of the desired product as pale yellow crystals.

Workup

  1. customAfter completion of the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. washthe resulting residue was washed with 10 ml of hexane

Sources & evidence

ORD record
ord-a237334d0ebe4447a39c78005867bc9c
Source dataset
uspto-grants-2016_09
Patent number
US09434684B2

Reaction notes

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