2-(Morpholin-4-yl)benzoic acid → HCID 66998773, compound

HRID 560505Notes

Reaction equation

HRID 560505 reaction equation
[NH2:1][CH2:2][C@H:3]1[N:8]([C:9]([C:11]2[N:12]=[C:13]([CH3:23])[S:14][C:15]=2[C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[O:10])[CH2:7][C@H:6]2[C@@H:4]1[CH2:5]2.[N:24]1([C:30]2[CH:38]=[CH:37][CH:36]=[CH:35][C:31]=2[C:32](O)=[O:33])[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[CH3:23][C:13]1[S:14][C:15]([C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[C:11]([C:9]([N:8]2[CH2:7][C@H:6]3[C@H:4]([CH2:5]3)[C@H:3]2[CH2:2][NH:1][C:32](=[O:33])[C:31]2[CH:35]=[CH:36][CH:37]=[CH:38][C:30]=2[N:24]2[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)=[O:10])[N:12]=1

Participants

3

Reactant 2

HCID 27765612-(Morpholin-4-yl)benzoic acidHCID 66998654((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone

Product 1

HCID 66998773HCID 66998773, compound

Procedure

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 2-Morpholin-4-yl-benzoic acid.

Sources & evidence

ORD record
ord-613cfad9ed28449f92dbddf5faf87c68
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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