HCID 25140790, compound → HCID 66997852, compound

HRID 560523Notes

Reaction equation

HRID 560523 reaction equation
[NH2:1][CH2:2][C@H:3]1[N:8]([C:9]([C:11]2[N:12]=[C:13]([CH3:23])[S:14][C:15]=2[C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[O:10])[CH2:7][C@H:6]2[C@@H:4]1[CH2:5]2.[O:24]1[C:33]2[CH:32]=[CH:31][CH:30]=[C:29]([C:34](O)=[O:35])[C:28]=2[CH:27]=[CH:26][CH2:25]1>>[CH3:23][C:13]1[S:14][C:15]([C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[C:11]([C:9]([N:8]2[CH2:7][C@H:6]3[C@H:4]([CH2:5]3)[C@H:3]2[CH2:2][NH:1][C:34]([C:29]2[C:28]3[CH:27]=[CH:26][CH2:25][O:24][C:33]=3[CH:32]=[CH:31][CH:30]=2)=[O:35])=[O:10])[N:12]=1

Participants

3

Reactant 2

HCID 25140790HCID 25140790, compoundHCID 66998654((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone

Product 1

HCID 66997852HCID 66997852, compound

Procedure

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 2H-Chromene-5-carboxylic acid.

Sources & evidence

ORD record
ord-fb1947dfa57845e88ea539d9a55c2398
Source dataset
uspto-grants-2011_11
Patent number
US08063099B2

Reaction notes

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