Benzyl Bromide → HCID 58031565, compound

Participants

Reaction Steps

Following the procedure as described in Example 5, making variations to replace benzyl bromide with 1-iodopropane to react with ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate, the title compound was obtained in 60% yield: 1H NMR (300 MHZ, CDCl3) δ 4.18 (q, J=7.2 Hz, 2H), 4.07-3.94 (m, 2H), 3.53-3.48 (m, 2H), 3.20 (t, J=7.2 Hz, 2H), 2.52 (s, 3H), 1.58-1.46 (m, 2H), 1.24 (t, J=7.2 Hz, 3H), 0.82 (t, J=7.2 Hz, 3H); MS (ES+) m/z 298.3 (M+1).

Provenance & Evidence