HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → Ethyl alpha-[3-(trifluoromethyl)benzylamino]-1-benzylindole-3-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Methyl alpha-[3-(trifluoromethyl)benzylamino]-1-benzylindole-3-acetate hydrochloride | HCID 67883724 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Ethyl alpha-[3-(trifluoromethyl)benzylamino]-1-benzylindole-3-acetate | HCID 19796621 | — |
Reaction Steps
To a magnetically stirred solution of methyl α-[3-(trifluoromethyl)benzylamino-]-1-benzylindole-3-acetate hydrochloride (100 mg) in 8 mL of ethanol was added 70 μL of 25% sodium methoxide in methanol. After stirring at room temperature for two hours, TLC analysis showed 90% conversion to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05245046 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-9d6b4639e61f428789f790c938140d8e |
| Source note | uspto-grants-1993_09 |