HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Cyano-5 fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester → 2-(4-Chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Cyano-5 fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 66999644 | — |
| Reactant | 2-(4-Fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000217 | — |
| Reactant | 2-(3,5-Dichloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000320 | — |
| Reactant | 2-(3-Chloro-4-fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000364 | — |
| Reactant | 2-(3-Chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000426 | — |
| Product | 2-(4-Chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000157 | — |
Reaction Steps
Applying the above procedure the following compounds were prepared: e.g. 2-(3-chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (MS (EI) M+=305.1); 2-(3-chloro-4-fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (MS (EI) M+=323.1); 2-(3,5-dichloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (MS (EI) M+=340.1); 2-(4-fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (MS (EI) M+=289.1); 2-(3-cyano-5 fluoro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (MS (EI) M+=314.2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063220B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-63204b58cfc940d1bba83c45962f5e3d |
| Source note | uspto-grants-2011_11 |