HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → HCID 178527342, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | 2-(4-Chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester | HCID 67000157 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 178527342 | HCID 178527342 | 48% |
Reaction Steps
The mixture of 2-(4-chloro-benzenesulfonyl)-3-ethoxy-acrylic acid methyl ester (7.62 g, 25 mmol) and 3-chloroaniline (3.19 g, 25 mmol) in diphenyl ether (20 ml) was heated at near reflux for 1 h. After cooling the precipitate was filtered and washed with ether to obtain 4.25 g of the title compound in 48.0% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063220B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-4ca2f9bd631840ac962cd3378c56a323 |
| Source note | uspto-grants-2011_11 |