HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → Ethyl 3-(benzylamino)-3-methylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Ethyl 3,3-dimethylacrylate | HCID 12516 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-(benzylamino)-3-methylbutanoate | HCID 288946 | 21.1% |
Reaction Steps
A solution of ethyl 3,3-dimethylacrylate (19.3 g, 0.151 mol) in EtOH (150 mL) was added benzylamine (16.2 g, 0.151 mol) and refluxed for 24 h. The reaction mixture was concentrated in vacuo. The distillation of the residue gave ethyl 3-benzylamino-3-methylbutyrate as a colorless oil (7.48 g, 21%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063221B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-319b932dd8ae4c888979a6e751abcd91 |
| Source note | uspto-grants-2011_11 |