Sodium Hydroxide → HCID 24989243, compound

Participants

Reaction Steps

The title compound was prepared in a similar manner as described in Example 7 (step 5) from ethyl (3-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetate and aqueous NaOH. 1H NMR (500 MHz, acetone-d6): δ7.97 (s, 1H), 7.62 (t, 1H), 7.12 (d, 1H), 6.94 (s, 1H), 6.75 (s, 1H), 5.22 (s, 2H), 4.91 (s, 1H), 3.82-3.75 (m, 2H), 3.63-3.57 (m, 2H), 2.16-2.07 (m, 2H), 1.94 (s, 2H). MS: m/z 466, 468 (MH+).

Provenance & Evidence