HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 59738181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86620463 | HCID 86620463 | — |
| Product | HCID 59738181 | HCID 59738181 | — |
Reaction Steps
The title compound was prepared in a similar manner as described in Example 7 (step 5) from ethyl (5-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetate and aqueous NaOH. 1H NMR (500 MHz, acetone-d6): δ7.68 (d, 1H), 7.62 (dd, 1H), 7.14-7.08 (m, 2H), 6.76 (td, 1H), 5.49 (s, 2H), 4.93-4.89 (m, 1H), 3.81-3.74 (m, 2H), 3.66-3.55 (m, 2H), 2.16-2.10 (m, 2H), 1.98-1.88 (m, 2H). MS: m/z 466, 468 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063224B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-2c1d6549be2b4d57a47500b259f69618 |
| Source note | uspto-grants-2011_11 |