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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 561220Generated: November 1, 2026

Sodium Hydroxide → HCID 59738181, compound

https://huagongshe.com/reaction/561220

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 86620463HCID 86620463—
ProductHCID 59738181HCID 59738181—

Reaction Steps

The title compound was prepared in a similar manner as described in Example 7 (step 5) from ethyl (5-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetate and aqueous NaOH. 1H NMR (500 MHz, acetone-d6): δ7.68 (d, 1H), 7.62 (dd, 1H), 7.14-7.08 (m, 2H), 6.76 (td, 1H), 5.49 (s, 2H), 4.93-4.89 (m, 1H), 3.81-3.74 (m, 2H), 3.66-3.55 (m, 2H), 2.16-2.10 (m, 2H), 1.98-1.88 (m, 2H). MS: m/z 466, 468 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063224B2
Source datasetuspto-grants-2011_11
ORD IDord-2c1d6549be2b4d57a47500b259f69618
Source noteuspto-grants-2011_11