Benzene → HCID 58260902, compound

Participants

Reaction Conditions

Reaction Steps

Benzene (70 mL) and compound 1 (6.63 g, 32.6 mmol) were combined. Then solid lithium diisopropylamide (4.01 g, 37.4 mmol) was added. The mixture was heated to 50° C. to form a cloudy red-orange solution. After a few hours the solution was filtered through diatomaceous earth to afford a clear yellow solution. The volatiles were evaporated to give a yellow solid. Pentane (15 mL) was added and the mixture was stirred briefly and then cooled to −10° C. overnight. The product was then collected on a glass frit and washed with pentane (2×20 mL) to give a white solid that was dried under reduced pressure. Yield: 5.50 g, 80.6%.

Provenance & Evidence