p-Anisoyl chloride → HCID 11351693, compound

Participants

Reaction Steps

To a solution of naphthalenyl amine (10) (65 mg, 0.2 mmol) in CH2Cl2 (5 mL) was added p-methoxybenzoyl chloride (45 uL, 0.24 mmol) and Et3N (50 uL, 0.4 mmol). The resultant solution was stirred at 25° C. overnight. The solvent was removed in vacuo and the residue was purified using HPLC to give the title compound (30 mg) as pale yellow solid. 1H NMR (300 MHz, MeOD) δ 8.73 (d, 1H), 8.08 (m, 4H), 7.70 (m, 3H), 7.10 (d, 2H), 6.90 (d, 2H), 6.70 (d, 2H), 3.84 (s, 3H), 3.60 (s, 3H); LC/MS m/z 463 (M+H)+.

Provenance & Evidence