HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-cyanophenylboronic acid → 4-Chloro-3-[5-[(2-cyclohexylethylamino)methyl]pyridin-2-yl]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-cyanophenylboronic acid | HCID 2763279 | — |
| Reactant | (6-Bromopyridin-3-ylmethyl)-(2-cyclohexylethyl)amine | HCID 59544849 | — |
| Product | 4-Chloro-3-[5-[(2-cyclohexylethylamino)methyl]pyridin-2-yl]benzonitrile | HCID 59544850 | — |
Reaction Steps
Using the procedure outlined in Preparation 13, (6-bromopyridin-3-ylmethyl)-(2-cyclohexylethyl)amine and 2-chloro-5-cyanophenyl boronic acid were converted to the title compound: RT=2.79 min; m/z (ES+)=354.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063247B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-e2a931c6ce8d45aab77ff6e34eebed71 |
| Source note | uspto-grants-2011_11 |