2,4-Difluorobenzaldehyde → alpha-Cyclopropyl-2,4-difluorobenZenemethanol

Participants

Reaction Steps

The title compound was prepared starting from 1.50 g (10.55 mmol) of 2,4-difluorobenzaldehyde and 31.7 ml (15.83 mmol) of a 0.5N solution of cyclopropylmagnesium bromide in tetrahydrofuran in analogy to the synthesis of the compound from Example 153A. 0.33 g (17% of theory) of the title compound was obtained.

Provenance & Evidence