HCID 58392447, compound → HCID 58392161, compound

HRID 561513Notes

Reaction equation

HRID 561513 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH:11]1[CH2:13][C:12]1([F:15])[F:14])[OH:10].[C:16](OC(C1CC1(F)F)C1C=CC(C(F)(F)F)=CC=1)(=[O:18])[CH3:17]>>[C:16]([O:10][CH:9]([C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH:11]1[CH2:13][C:12]1([F:15])[F:14])(=[O:18])[CH3:17]

Participants

3

Reactant 2

HCID 58392447HCID 58392447, compoundHCID 58392460HCID 58392460, compound

Product 1

HCID 58392161HCID 58392161, compound

Procedure

The title compound was prepared starting from 8.20 g (32.4 mmol) of a mixture of the two diastereomers of the compound from Example 191A in analogy to the synthesis of the compound from Example 192A. 7.70 g (81% of theory) of the title compound were obtained.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-ed3db57458ae4f6796c3876957ee2e72
Source dataset
uspto-grants-2011_11
Patent number
US08063234B2

Reaction notes

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