HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(1-benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propanoate → 3-(1-Benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(1-benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propanoate | HCID 58392303 | — |
| Reactant | 3-(4-Chlorophenyl)-3-{6-fluoro-7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propan-1-ol | HCID 58392341 | — |
| Product | 3-(1-Benzothiophen-5-yl)-3-{7-[(methylsulfanyl)methyl]-1H-indol-3-yl}propan-1-ol | HCID 58392466 | — |
Reaction Steps
The title compound was prepared starting from 1.17 g (2.87 mmol) of the compound from Example 49A in analogy to the synthesis of the compound from Example 16. 0.93 g (88% of theory) of the title compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063234B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-2e36c08cd9894d479ab66538406e337e |
| Source note | uspto-grants-2011_11 |