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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56158Generated: October 30, 2026

HCID 28972568, compound → 2-fluoro-N1-(2-morpholinoethyl)benzene-1,4-diamine

https://huagongshe.com/reaction/56158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 28972568HCID 28972568—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product2-fluoro-N1-(2-morpholinoethyl)benzene-1,4-diamineHCID 1760969094%

Reaction Steps

To a solution of 2-fluoro-N-(2-morpholinoethyl)-4-nitroaniline (0.60 g, 2.23 mmol) in THF (8.0 mL) was added catalyst Pd/C (0.03 g). The reaction mixture was stirred at rt under H2 overnight, then filtered. The filtrate was concentrated in vacuo to give the title compound as yellow oil (0.50 g, 94%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434695B2
Source datasetuspto-grants-2016_09
ORD IDord-ceb74fd6c07a4d9aa90d96551da23d0d
Source noteuspto-grants-2016_09