HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 28972568, compound → 2-fluoro-N1-(2-morpholinoethyl)benzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 28972568 | HCID 28972568 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-fluoro-N1-(2-morpholinoethyl)benzene-1,4-diamine | HCID 17609690 | 94% |
Reaction Steps
To a solution of 2-fluoro-N-(2-morpholinoethyl)-4-nitroaniline (0.60 g, 2.23 mmol) in THF (8.0 mL) was added catalyst Pd/C (0.03 g). The reaction mixture was stirred at rt under H2 overnight, then filtered. The filtrate was concentrated in vacuo to give the title compound as yellow oil (0.50 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-ceb74fd6c07a4d9aa90d96551da23d0d |
| Source note | uspto-grants-2016_09 |