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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56162Generated: October 25, 2026

3-chloro-N-(2-morpholinoethyl)-4-nitroaniline → 3-chloro-N1-(2-morpholinoethyl)benzene-1,4-diamine

https://huagongshe.com/reaction/56162

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-chloro-N-(2-morpholinoethyl)-4-nitroanilineHCID 90023325—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
Product3-chloro-N1-(2-morpholinoethyl)benzene-1,4-diamineHCID 90022535—

Reaction Steps

To a solution of 3-chloro-N-(2-morpholinoethyl)-4-nitroaniline (3.50 g, 12.25 mmol) in EtOAc (60 mL) was added catalyst Pd/C (0.73 g). The reaction was stirred at rt under H2 overnight, then filtered. The filtrate was concentrated in vacuo to give the crude product for the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434695B2
Source datasetuspto-grants-2016_09
ORD IDord-93ebbf072ed644d4967deae5a740e95e
Source noteuspto-grants-2016_09