HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-chloro-N-(2-morpholinoethyl)-4-nitroaniline → 3-chloro-N1-(2-morpholinoethyl)benzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-chloro-N-(2-morpholinoethyl)-4-nitroaniline | HCID 90023325 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-chloro-N1-(2-morpholinoethyl)benzene-1,4-diamine | HCID 90022535 | — |
Reaction Steps
To a solution of 3-chloro-N-(2-morpholinoethyl)-4-nitroaniline (3.50 g, 12.25 mmol) in EtOAc (60 mL) was added catalyst Pd/C (0.73 g). The reaction was stirred at rt under H2 overnight, then filtered. The filtrate was concentrated in vacuo to give the crude product for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-93ebbf072ed644d4967deae5a740e95e |
| Source note | uspto-grants-2016_09 |