Trifluoroacetic acid → HCID 58392302, compound

Participants

Reaction Steps

0.02 ml (0.24 mmol) of trifluoroacetic acid was added to 50.0 mg (0.20 mmol) of the compound from Example 136A and 35.7 mg (0.20 mmol) of the compound from Example 8A in 4 ml of dichloromethane, and the mixture was stirred at RT overnight. It was concentrated, and the residue was purified by preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient with addition of 0.1% formic acid) to result in 10.0 mg (12% of theory) of the title compound as mixture of diastereomers.

Provenance & Evidence