Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Chloro-4-fluorophenyl)(4-chlorophenyl)methanol → 3-[(3-Chloro-4-fluorophenyl)(4-chlorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Chloro-4-fluorophenyl)(4-chlorophenyl)methanol | HCID 2758103 | — |
| 반응물 | 3-[Bis(4-fluorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole | HCID 58392127 | — |
| 반응물 | 7-[(Methylsulfanyl)methyl]-1H-indole | HCID 58392187 | — |
| 생성물 | 3-[(3-Chloro-4-fluorophenyl)(4-chlorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indole | HCID 58392241 | — |
반응 단계
The title compound was prepared starting from 750 mg (4.23 mmol) of the compound from Example 8A and 1.15 g (4.23 mmol) of the compound from Example 177A in analogy to the synthesis of the compound from Example 278. 483 mg (26% of theory) of the target compound were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063234B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-624db7f2ef884e08b61626cafb8e9085 |
| 출처 메모 | uspto-grants-2011_11 |