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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 561706Generated: October 30, 2026

1-(4-Chlorophenyl)-1-(4-fluorophenyl)ethanol → HCID 58392090, compound

https://huagongshe.com/reaction/561706

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chlorophenyl)-1-(4-fluorophenyl)ethanolHCID 13511683—
Reactant3-[Bis(4-fluorophenyl)methyl]-7-[(methylsulfanyl)methyl]-1H-indoleHCID 58392127—
Reactant7-[(Methylsulfanyl)methyl]-1H-indoleHCID 58392187—
ProductHCID 58392090HCID 58392090—

Reaction Conditions

Temperature80 °C

Reaction Steps

The title compound was prepared starting from 1.00 g (5.64 mmol) of the compound from Example 8A and 1.41 g (5.64 mmol) of the compound from Example 182A in analogy to the synthesis of the compound from Example 278. A difference was that stirring at 80° C. was for only 4 h. 1.31 g (56% of theory) of the target compound were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063234B2
Source datasetuspto-grants-2011_11
ORD IDord-154f3c784501405e9b764ffb2d623369
Source noteuspto-grants-2011_11