Hydrogen Peroxide → HCID 54671347, compound

Participants

Reaction Steps

(Z)-4-(1-(4-(2-(6-(4,4,5,5,5-pentafluoropentylthio)hexylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol from the previous reaction is dissolved in ethyl acetate and acetic acid. To this solution is added hydrogen peroxide solution in water. The mixture is stirred until the reaction is complete (TLC). Excess hydrogen peroxide is destroyed by addition of sodium sulfite solution in water. The phases are separated and the aqueous phase is washed with ethyl acetate. The combined organic phases are dried over sodium sulfate, filtered and concentrated under reduced pressure to afford (Z)-4-(1-(4-(2-(6-(4,4,5,5,5-pentafluoropentylsulfinyl)hexylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol among other products.

Provenance & Evidence