Ethanamine, 2,2,2-trifluoro- → N-[(2,3-Dichlorophenyl)methyl]-2,2,2-trifluoroethan-1-amine

HRID 561815Notes

Reaction equation

HRID 561815 reaction equation
[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.[F:11][C:12]([F:16])([F:15])[CH2:13][NH2:14]>>[Cl:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][NH:14][CH2:13][C:12]([F:16])([F:15])[F:11]

Participants

3

Reactant 2

HCID 9773Ethanamine, 2,2,2-trifluoro-HCID 357452,3-Dichlorobenzaldehyde

Product 1

HCID 28371068N-[(2,3-Dichlorophenyl)methyl]-2,2,2-trifluoroethan-1-amine

Procedure

Amine 27 was prepared according to the reaction sequence described for Amine 3, but using instead 2,3-dichlorobenzaldehyde as the starting aldehyde and 2,2,2-trifluoroethylamine as the starting amine. The title compound was isolated as a colorless oil.

Sources & evidence

ORD record
ord-7fc2ae64a4174796ae57f4be8f12efd9
Source dataset
uspto-grants-2011_11
Patent number
US08063105B2

Reaction notes

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