HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[1-(Piperidin-1-yl)cyclohexyl]methanamine → HCID 16038208, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[1-(Piperidin-1-yl)cyclohexyl]methanamine | HCID 398402 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(3-formylphenyl)-1H-indole-7-carboxamide | HCID 57732804 | — |
| Product | HCID 16038208 | HCID 16038208 | 34.7% |
Reaction Steps
Following the general procedure of example 16, 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-(3-formylphenyl)-1H-indole-7-carboxamide (50 mg, 0.114 mmol), 1-[1-(1-piperidinyl)cyclohexyl]methanamine (17 mg, 0.087 mmol) and NaBH(OAc)3 (58 mg, 0.261 mmol) were reacted to give the title compound (18.7 mg, 27%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063071B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-4db0c354b15b4b0f870bcad2678e097d |
| Source note | uspto-grants-2011_11 |