HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → (Z)-3-amino-N-(3-cyano-4-(dihexylamino)phenyl)but-2-enamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | N-(3-cyano-4-(dihexylamino)phenyl)-3-oxobutanamide | HCID 90023598 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (Z)-3-amino-N-(3-cyano-4-(dihexylamino)phenyl)but-2-enamide | HCID 90022969 | 88% |
Reaction Steps
A mixture of N-(3-cyano-4-(dihexylamino)phenyl)-3-oxobutanamide (1.47 g, 3.81 mmol), MeOH (15 mL) and ammonia (15 mL) was stirred at rt overnight. The mixture was concentrated in vacuo to give the title compound as black oil (1.30 g, 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-af8d51602c5843c0afb91c84da09b43c |
| Source note | uspto-grants-2016_09 |