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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 56215Generated: October 25, 2026

2-Furanpropionic acid → 3-(Oxolan-2-yl)propanoic acid

https://huagongshe.com/reaction/56215

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furanpropionic acidHCID 70286—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product3-(Oxolan-2-yl)propanoic acidHCID 263161—

Reaction Conditions

Temperature60 °C

Reaction Steps

A mixture of 3-(furan-2-yl)propanoic acid (11.0 g, 80.0 mmol) and Pd/C (1.1 g, 10%) in MeOH (110 mL) was stirred at 60° C. under 30 bar of H2 overnight. The mixture was then filtered and the filtrate was concentrated in vacuo to give the title compound, which was used for next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09434695B2
Source datasetuspto-grants-2016_09
ORD IDord-9f3c11f0258740c08bd5d0b5b6d2e178
Source noteuspto-grants-2016_09