HRID562329

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID180

Acetone

C3H6O

HCID42630498

未命名化合物

PRODUCTS

产物

HCID42630620

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the general procedure of 3-[1-(ethylsulfonyl)-4-piperidinyl]-5-[2-(1-methylethyl)-2,3-dihydro-1H-isoindol-5-yl]-1H-indole-7-carboxamide, substituting cyclopentanone (17 mg, 0.198 mmol) for 2-propanone to afford 4.8 mg of the title compound.

WORKUP

后处理

customThe title compound was prepared

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-31101e42d83043759c75249909d5176e
来源数据集: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08063071B2
来源说明: uspto-grants-2011_11

反应SMILES

[CH2:1]([S:3]([N:6]1[CH2:11][CH2:10][CH:9]([C:12]2[C:20]3[C:15](=[C:16]([C:33]([NH2:35])=[O:34])[CH:17]=[C:18]([C:21]4[CH:22]=[C:23]5[C:27](=[CH:28][CH:29]=4)[CH2:26][N:25]([CH:30]([CH3:32])[CH3:31])[CH2:24]5)[CH:19]=3)[NH:14][CH:13]=2)[CH2:8][CH2:7]1)(=[O:5])=[O:4])[CH3:2].[CH3:36][C:37](=O)C>>[CH:30]1([N:25]2[CH2:24][C:23]3[C:27](=[CH:28][CH:29]=[C:21]([C:18]4[CH:19]=[C:20]5[C:15](=[C:16]([C:33]([NH2:35])=[O:34])[CH:17]=4)[NH:14][CH:13]=[C:12]5[CH:9]4[CH2:8][CH2:7][N:6]([S:3]([CH2:1][CH3:2])(=[O:4])=[O:5])[CH2:11][CH2:10]4)[CH:22]=3)[CH2:26]2)[CH2:31][CH2:37][CH2:36][CH2:32]1