HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfur dichloride → 3-(3-Fluorophenyl)propanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfur dichloride | HCID 25353 | — |
| Reactant | 3-(3-Fluorophenyl)propionic acid | HCID 2737489 | — |
| Product | 3-(3-Fluorophenyl)propanoyl chloride | HCID 18993501 | — |
Reaction Steps
A mixture of 3-(3-fluorophenyl)propanoic acid (2.50 g, 14.9 mmol) and dichlorosulfane (10 mL) under N2 was refluxed for 3 h. The mixture was cooled to rt and concentrated in vacuo to give the title compound, which was used for next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-119617a6c7804e7aa0f70ecb08b9ebb9 |
| Source note | uspto-grants-2016_09 |