HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfur dichloride → 4-(3-Fluorophenoxy)butanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfur dichloride | HCID 25353 | — |
| Reactant | 4-(3-Fluorophenoxy)butanoic acid | HCID 6486015 | — |
| Product | 4-(3-Fluorophenoxy)butanoyl chloride | HCID 90023167 | — |
Reaction Steps
A solution of 4-(3-fluorophenoxy)butanoic acid (3.00 g, 15.1 mmol) in dichlorosulfane (15 mL) under N2 was refluxed for 3 h. The mixture was cooled to rt and concentrated in vacuo to give the title compound, which was used for next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434695B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-f4e72ac7cd384758b6534f103e26e766 |
| Source note | uspto-grants-2016_09 |