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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562723Generated: October 31, 2026

1,4-Dibromobutane → 2-(Butyloxy)-9-[4-(hexahydro-1H-azepin-yl)butyl]-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/562723

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
ReactantAzepaneHCID 8119—
Reactant9-[3-(1-Azetidinyl)propyl]-2-(butyloxy)-8-(methyloxy)-9H-purin-6-amineHCID 59252600—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-9-[4-(hexahydro-1H-azepin-yl)butyl]-8-(methyloxy)-9H-purin-6-amineHCID 59252619—

Reaction Steps

Prepared similarly to Intermediate 20 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate, 1,4-dibromobutane and hexahydro-1H-azepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067426B2
Source datasetuspto-grants-2011_11
ORD IDord-0b4d7cef7f3c437981f7f28f2ae1a95c
Source noteuspto-grants-2011_11