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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562725Generated: November 1, 2026

Pyrrolidine → 2-(Butyloxy)-8-(methyloxy)-9-[5-(1-pyrrolidinyl)pentyl]-9H-purin-6-amine

https://huagongshe.com/reaction/562725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant9-[5-(1-Azetidinyl)pentyl]-2-(butyloxy)-8-(methyloxy)-9H-purin-6-amineHCID 59252625—
Reactant2-(Butyloxy)-9-(5-chloropentyl)-8-(methyloxy)-9H-purin-6-amineHCID 59252636—
Product2-(Butyloxy)-8-(methyloxy)-9-[5-(1-pyrrolidinyl)pentyl]-9H-purin-6-amineHCID 59252570—

Reaction Steps

Prepared similarly to Intermediate 27 from 2-(butyloxy)-9-(5-chloropentyl)-8-(methyloxy)-9H-purin-6-amine and pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067426B2
Source datasetuspto-grants-2011_11
ORD IDord-d65261a6313546eb9a5660937dacf976
Source noteuspto-grants-2011_11